Science news related to the project

Nowadays we are living in quite uncertain world where the threat of terrorist attacks is constantly increasing. Moreover, the menace of local wars is present almost everywhere in the world. Therefore, it is of primary interest for authorities to increase and optimize all possible resources in order to counteract these threats. As very recent history has showed that even nowadays these threats are unavoidable which makes it quite important to measure and evaluate the outcomes of already accomplished terrorist acts or war activities on human health and moreover, the long lasting effect on future generations. This implies implementation of adequate countermeasures for minimizing and diminishing of all dangerous consequences of terrorist and military activities.

The research groups that take part in the execution of this research have great expertise in bioengineering, biotechnology and genotoxicity testing which is proven by the large number of scientific papers published by them on the topic (Celik et al., 2009; El Idrissi et al., 2013; Genc et al., 2014; Georgieva et al., 2015a; Georgieva et al., 2015b; Hong et al., 2012; Jansen and Ruskovska, 2015; Miloshev et al., 2002; Ruskovska et al., 2014; Staneva et al., 2016). All four co-directors will supervise, manage and control the whole research scientific work during this phase as well as will supervise the young researchers during their project participation. Two young researches from Prof. Miloshev’s lab, two from Prof. Shen’s department, four from the laboratory of Prof. Ruskovska and two from the department of Prof. Celík will be involved in this part of project development. Their involvement will mainly include research and training. All young researchers will be responsible for the application of the techniques for bioengineering of live cells in order to make them sense illicit compounds and genotoxins at high speed and in miniscule concentrations. Short exchange training activities are foreseen for any one of them in other’s laboratory in order to gain experience and become apt at different techniques and moreover, to be able to gain and exchange knowledge and expertise. The affiliated member the Atlantic Club in Bulgaria will take care of the whole logistics of this sub-project phase, conveying good communication and collaboration among all project teams by organizing, managing and monitoring all steps of work by regular get-together events, online communication and coordination. Two young participants from Dr. Passy’s team will also participate in all these activities by regular involvement in all work concerning these communicational and logistic activities.

Scientific news

Milestone 4

https://www.marica.bg/ucheni-ot-medicinskiq-izpylnqvat-proekt-po-programa-na-nato-Article-220252.html?fbclid=IwAR3B9tDpUgZykwK0PAw2Rz6GT-RG8oQKfKLutU8k60ZZYbmVggB-dUGOC2w

https://www.glas.bg/1918625/mu-plovdiv-domakin-na-sresha-po-nauchna-programa-na-nato?fbclid=IwAR1cToXc_XQ14x1FXby-CzawnnT4QgVxbfYEPw8V7RAlal8U3JPHDSrwyyo

http://www.bta.bg/bg/c/BO/id/2022732

Milestone 3

ORIGINAL ARTICLES

Krasteva, N., Keremidarska-Markova, M., Hristova-Panusheva, K., Andreeva, T., Speranza, G., Wang, D., Draganova-Filipova, M., Miloshev, G. and Georgieva, M. (2019). Aminated graphene oxide as a potential new therapy for colorectal cancer, Oxidative Medicine and Cellular Longevity (in press).

Miloshev, G., Staneva, D., Uzunova, K., Vasileva, B., M., Draganova-Filipova,   Zagorchev, P. , Georgieva, M. (2019). Linker histones and chromatin remodelling complexes maintain genome stability and control cellular ageing, Mechanismsm of Ageing and Development (177): 55-65: S0047-6374(18)30051-4. doi: 10.1016/j.mad.2018.07.002

https://www.sciencedirect.com/science/article/pii/S0047637418300514?via%3Dihub

Basu, P.; Saha, N.; Alexandrova, R.; Andonova-Lilova, B.; Georgieva, M.; Miloshev, G.; Saha, P. (2018). Biocompatibility and Biological Efficiency of Inorganic Calcium Filled Bacterial Cellulose Based Hydrogel Scaffolds for Bone Bioengineering. Int. J. Mol. Sci., 19, 3980. https://doi.org/10.3390/ijms19123980

https://www.mdpi.com/1422-0067/19/12/3980

 

ATTENDED CONFERENCES

32ND LANGENARGENER SYMPOSIUM DES BODENSEEFORUMS, ROTKREUZHAUS BREGENZ – 7-8TH DECEMBER, 2018

Miloshev talk: ▪ Field Detector of Genotoxic Activity

 

20-TH JUBILEE INTERNATIONAL SCHOOL ON CONDENSED MATTER PHYSICS – 3RD – 7TH SEPT., 2018, VARNA

Poster: ▪Dose-dependent genotoxicity of ammonia-modified graphene oxide particles in lung cancer cells

 

SECOND YOUNG SCIENTISTS SEMINAR ON GENETICS WITH INTERNATIONAL PARTICIPATION – 3RD – 5TH OCTOBER, SOFIA, BULGARIA

Talk: ▪ H. rhodopensis extracts influence genome activity of cell aiding it to cope with damaging effects

Poster: ▪ Assessment of the damages caused by anthropogenic pollution in the genome of the Black sea mussel

 

BIOMATERIALS INTERNATIONAL 2018 – 22ND – 25TH JULY, 2018, TOKYO, JAPAN

Poster: ▪ An intelligent “ready-to-use” system for field-employable genotoxicity surveillance

Poster: ▪ Cytotoxicity and genotoxicity effect of ammonia-functionalized graphene oxide nanoparticles in a colon adenocarcinoma cell line

 

CELL SYMPOSIA: AGING AND METABOLISM 2018 – 23RD – 25TH SEPT., SITGES, BARCELONA, SPAIN

Poster: ▪ UVA/B stress differently influences cells during their ageing

 

Milestone 2

Original articles

Georgieva,,Staneva, D.and Miloshev, G. (2017). TeleGenetics – Bringing Telemedicine Closer to the New Era of Personalized Medicine, In Benchmarking Telemedicine: Improving Health Security in the Balkans, IOS press, Editor Stone, C.S., pp: 42-48; ISBN print 978-1-61499-811-2; ISBN online 978-1-61499-812-9; https://www.iospress.nl/book/benchmarking-telemedicine-improving-health-security-in-the-balkans/

Miloshev, G., Staneva, D. and Georgieva, M. (2017). Genetics and Epigenetics in Telemedicine, In Benchmarking Telemedicine: Improving Health Security in the Balkans, IOS press, Editor Stone, C.S., pp:37-41; ISBN print 978-1-61499-811-2; ISBN online 978-1-61499-812-9; http://ebooks.iospress.nl/volumearticle/47765

Attended conferences

IUBMB FOCUSED MEETING ON “MOLECULAR ASPECTS OF AGEING AND LONGEVITY” – 16 – 19TH OCTOBER, ATHENS, GREECE

Poster: ▪ Epigenetic role of higher-order chromatin organization in cellular aging

WORLD BIODISCOVERY CONGRESS: 17 – 19TH JULY 2017, SOFIA, ▪ Comet assay – a sensitive tool for genotoxicity assessment of environmental stress in Mytilus galloprovincialis from the Bulgarian Black Sea coast